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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vguit</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник Воронежского государственного университета инженерных технологий</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of the Voronezh State University of Engineering Technologies</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-910X</issn><issn pub-type="epub">2310-1202</issn><publisher><publisher-name>VSUET</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20914/2310-1202-2018-3-185-189</article-id><article-id custom-type="elpub" pub-id-type="custom">vguit-1947</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Пищевая  биотехнология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Food biotechnology</subject></subj-group></article-categories><title-group><article-title>Специализированный продукт в форме БАД для коррекции обменных нарушений нервной системы</article-title><trans-title-group xml:lang="en"><trans-title>Biologically active complex multifactorial support of the central nervous system</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тохириён</surname><given-names>Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Tohiriyon</surname><given-names>B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.т.н., доцент, кафедра товароведения и экспертизы, 8- марта, 62, г. Екатеринбург, 620019, Россия</p></bio><bio xml:lang="en"><p>Cand. Sci. (Engin.), associate professor, Department of Commodity Research and Expertise, 8th of March, 62, Ekaterinburg, 620019, Russia</p></bio><email xlink:type="simple">tohiriyoni@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Позняковский</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Poznyakovskii</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.б.н., профессор, кафедра Технологии питания, ул. 8-марта, 62, г. Екатеринбурн, 620019, Россия</p></bio><bio xml:lang="en"><p>Dr. Sci. (Biol.), professor, department of nutrition technology, March 8, 62, Ekaterinburg, 620019, Russia</p></bio><email xlink:type="simple">pvm1947@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Уральский государственный экономический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural State Economic University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Уральский государственный экономический университет</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Ural state University of Economics</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>26</day><month>09</month><year>2018</year></pub-date><volume>80</volume><issue>3</issue><fpage>185</fpage><lpage>189</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тохириён Б., Позняковский В.М., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Тохириён Б., Позняковский В.М.</copyright-holder><copyright-holder xml:lang="en">Tohiriyon B., Poznyakovskii V.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-vsuet.ru/vguit/article/view/1947">https://www.vestnik-vsuet.ru/vguit/article/view/1947</self-uri><abstract><p>Разработана новая таблетированная форма биологически активной добавки для коррекции обменных нарушений нервной системы – БАД «Софиа». Особенности технологии указанной формы БАД заключаются в предотвращении окислительных процессов рецептурных ингредиентов за счет незначительного количества влаги и исключения активного воздействия кислорода. Биологически активный комплекс способен активизировать запоминание и воспроизведение информации, скорость мышления и уровень общего энергетического потенциала за счет улучшения работы центральной нервной системы. Сбалансированный комплекс растительных компонентов используемых для получения нового вида БАД – экстракт гинкго билоба, валериана, лимонник китайский, пустырник позволяет достичь необходимого эффекта, при котором проявляется выраженное действие названных компонентов. Перечисленные компоненты тонизирует трофику нервной системы, улучшает обменные процессы, способствуют нормализации и профилактике повышенного артериального давления. Наличие в составе нового вида БАД аминокислот (незаменимые и заменимые): цистеин, триптофан, глицин, фенилаланин, тирозин и глютаминовая кислота, выполняет роль нейромедиатора в ЦНС, позволяет регулировать углеводно-жировой обмен, ускорять процесс передачи импульса по нервному волокну, не допуская при этом перевозбуждения. Подавляющее большинство входящих аминокислот свойственно антидепрессивное действие. Входящий в рецептурный состав нового вида БАД витамины группы В способствуют насыщению энергией, обеспечивая ее максимальное использование нервной тканью, а также восстановлению структуры нервной ткани. Установлены регламентируемые показатели пищевой ценности специализированного продукта, определяющие его функциональную направленность. Эффективность подтверждена клиническими испытаниями на группе больных с вегето-сосудистой дистонией. Показано гигиеническое благополучие разработанного продукта, установлены сроки и режимы хранения, проведена промышленная апробация.</p></abstract><trans-abstract xml:lang="en"><p>Developed a new tablet form BAA multifactorial support the central nervous system - BAA «Sophia». Technology features of this form of BAA are the prevention of oxidative processes of compounding ingredients at the expense of a small amount of moisture and eliminating active oxygen exposure. Biologically active complex is able to activate the memorization and reproduction of information, speed of thinking and the level of total energy capacity by improving the work of the central nervous system. A balanced combination of active principles (schisandrachinensis, Ginkgo biloba) and sedatives (Valerian, motherwort) of plant components allows to achieve the effect of fine-tuning, which is very well manifested the effect of these components. The ingredients improve nervous tissue trophism, tonus of brain vessels, normalizes venous outflow and contribute to the prevention of high blood pressure. The presence of complex essential and non-essential amino acids such as tryptophan, glycine, tyrosine and glutamic acid, to regulate the synthesis of neurotransmitters in the Central nervous system, molecular basis of memory, to optimize carbohydrate and fat metabolism, accelerate the process of impulse transmission along the nerve fiber, while avoiding overstimulation. For most incoming amino acids typical antidepressant effects. Part of the complex Inositol is one of the main nutritional components of nervous tissue, which helps to restore its structure. B vitamins contribute to the saturation energy, I guarantee its maximum use by the nervous tissue. Installed regulated indicators of food value of the specialized product that determine its functional orientation. The effectiveness is confirmed by clinical tests in the group of patients with dystonia. Shown hygienic well-being of the developed product, periods and modes of storage of spent industrial testing.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>центральная нервная система</kwd><kwd>комплексная терапия</kwd><kwd>функциональная направленность</kwd><kwd>эффективность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>biologically active food supplement</kwd><kwd>supplement formula</kwd><kwd>central nervous system</kwd><kwd>complex therapy</kwd><kwd>functional properties</kwd><kwd>efficacy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Уральский государственный экономический университет</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Австриевских А.Н., Вековцев А.А., Позняковский В.М. Продукты здорового питания: новые технологии, обеспечение качества, эффективность применения. Новосибирск: Сиб. унив. изд-во, 2005. 416 с.</mixed-citation><mixed-citation xml:lang="en">Avstrievskikh A.N. Produkty zdorovogo pitaniia novye tekhnologii obespechenie kachestva effektivnost primeneniia [Healthy nutrition products: new technologies, quality assurance, efficacy] Novosibirsk, Siberian University Publishing House, 2005. 416 p. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Кондратьев А.В, Шнайдер Н.А., Шульмин А.В. Эпидемиология головных болей // Современные проблемы науки и образования. 2015. № 6. С. 23.</mixed-citation><mixed-citation xml:lang="en">Kondratiev A.V., Shneider N.A., Shulmin A.V. Headache epidemiology. Sovremennye problemy nauki i obrazovaniia [Modern science and education problems] 2015. no. 6. pp. 23 (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Лебедева Е.Р., Кобзева Н.Р., Гилев Д.В., Олесен Д. Анализ организации медицинской помощи и ведения больных с первичными головными болями // Уральский медицинский журнал. 2014. № 6(120). С. 174–182.</mixed-citation><mixed-citation xml:lang="en">Lebedeva E.R., Kobzeva N.R., Gilyov D.V., Olesen D. Health care organization analysis and management of patients with primary headaches. Uralskii meditsinskii zhurnal [Ural Medical Journal] 2014. no.  6(120). pp. 174–182. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Осипова В.В., Азимова Ю.Э., Табеева Г.Р. и др. Диагностика головных болей в России и странах постсоветского пространства: состояние проблемы и пути её решения // Анналы клинической и экспериментальной неврологии. 2012. Т. 6. № 2. С. 16–22.</mixed-citation><mixed-citation xml:lang="en">Osipova V.V., Azimova Yu.E., Tabeeva G.R., et al. Headache diagnosis in Russia and former Soviet republics: problems and solutions. Annaly klinicheskoi i eksperimentalnoi nevrologii [Annals of clinical and experimental neurology]. 2012. vol. 6. no. 2. pp. 16–22. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Lafaille F.G. et al. Impaired intrinsic immunity to HSV1 in human iPSC-derived TLR3deficient CNS cells //Nature. 2012. V. 91(7426). P.769–773.</mixed-citation><mixed-citation xml:lang="en">Lafaille F.G. et al. Impaired intrinsic immunity to HSV1 in human iPSC-derived TLR3deficient CNS cells. Nature. 2012. vol. 91(7426). pp.769–773.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lund N., Westergaard M.L., Barloese M. et al. Epidemiology of concurrent headache and sleep problems in Denmark // Cephalalgia. 2014. V. 34. № 10. P. 833–845.</mixed-citation><mixed-citation xml:lang="en">Lund N., Westergaard M.L., Barloese M. et al. Epidemiology of concurrent headache and sleep problems in Denmark. Cephalalgia. 2014. vol. 34. no. 10. pp. 833–845.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Челнакова Н.Г., Позняковский В.М. Питание и здоровье современного человека. М.: Изд-во «Старые русские», 2015. 224 с.</mixed-citation><mixed-citation xml:lang="en">Chelnakova N.G., Poznyakovsky V.M.  Pitanie i zdorove sovremennogo cheloveka [Contemporary people nutrition and health] Мoscow, Publishing House «Old Russians», 2015.224 p. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Stovner L, Hagen K, Jensen R, Katsarava Z. et al. The global burden of 353 headache: a documentation of headache prevalence and disability worldwide // Cephalalgia. 2007. V. 27(3). P. 193–210.</mixed-citation><mixed-citation xml:lang="en">Stovner L, Hagen K, Jensen R, Katsarava Z. et al. The global burden of 353 headache: a documentation of headache prevalence and disability worldwide. Cephalalgia. 2007. vol. 27(3). pp. 193–210.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mirmiran P., Bahadoran, Z., Azizi F. Functional foods-based diet as a novel dietary approach for management of type 2 diabetes and its complications: A review // World J. Diabetes 2014. № 5. P. 267–281.</mixed-citation><mixed-citation xml:lang="en">Mirmiran P., Bahadoran, Z., Azizi F. Functional foods-based diet as a novel dietary approach for management of type 2 diabetes and its complications: A review. World J. Diabetes 2014. no. 5. pp. 267–281.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Fulgoni V.L.III, Keast D.R., Bailey R.L., Dwyer J. Foods, fortificants, and supplements: Where do Americans get their nutrients? // J. Nutr. 2011. № 141. Р. 1847–1854.</mixed-citation><mixed-citation xml:lang="en">Fulgoni V.L.III, Keast D.R., Bailey R.L., Dwyer J. Foods, fortificants, and supplements: Where do Americans get their nutrients?  J. Nutr. 2011. no. 141. pp. 1847–1854.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Fenech M., El-Sohemy A., Cahill L., Ferguson L.R. et al. Nutrigenetics and nutrigenomics: Viewpoints on the current status and applications in nutrition research and practice // J. Nutr. Nutr. 2011. V. 4. P. 69–89.</mixed-citation><mixed-citation xml:lang="en">Fenech M., El-Sohemy A., Cahill L., Ferguson L.R. et al. Nutrigenetics and nutrigenomics: Viewpoints on the current status and applications in nutrition research and practice. J. Nutr. Nutr. 2011. vol. 4. pp. 69–89.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Gemming L., Jiang Y., Swinburn B., Utter J. et al. Under-reporting remains a key limitation of self-reported dietary intake: An analysis of the 2008/09 New Zealand Adult Nutrition survey // Eur. J. Clin. Nutr. 2013. P. 259–264.</mixed-citation><mixed-citation xml:lang="en">Gemming L., Jiang Y., Swinburn B., Utter J. et al. Under-reporting remains a key limitation of self-reported dietary intake: An analysis of the 2008/09 New Zealand Adult Nutrition survey. Eur. J. Clin. Nutr. 2013. pp. 259–264.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Witte K.K., Byrom R. Micronutrients for chronic heart failure: End of the road or path to enlightenment? // JACC Heart Fail. 2014. № 2. P. 318–320.</mixed-citation><mixed-citation xml:lang="en">Witte K.K., Byrom R. Micronutrients for chronic heart failure: End of the road or path to enlightenment? JACC Heart Fail. 2014. no. 2. pp. 318–320.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Mozaffarian D., Ludwig D.S. Dietary guidelines in the 21st century – A time for food // JAMA 2010. № 304. P 681–682.</mixed-citation><mixed-citation xml:lang="en">Mozaffarian D., Ludwig D.S. Dietary guidelines in the 21st century – A time for food. JAMA 2010. no. 304. pp. 681–682.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Герасименко Н.Ф., Позняковский В.М., Челнакова Н.Г Здоровое питание и его роль в обеспечение качества жизни // Технологии пищевой и перерабатывающей пром-ти АПК – продукты здорового питания. 2016.№ 4 (12).С. 52–57</mixed-citation><mixed-citation xml:lang="en">Gerasimenko N.F., Poznyakovsky V.M., Chelnakova N.G. Healthy nutrition and its role in life quality assurance. Tekhnologii pishchevoi i pererabatyvaiushchei prom-ti APK produkty zdorovogo pitaniia [Technologies of food and processing industry in agribusiness – healthy nutrition products] 2016. no. 4(12). pp. 52–57 (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Здоровье России: Атлас. М.:НЦССХ им. А.Н.Бакулева РАМН, 2012. 408 с.</mixed-citation><mixed-citation xml:lang="en">Zdorove Rossii Atlas [Russia’s health: Atlas / Edited by Bokeria L.A. 8th edition] Moscow, Bakoulev Centre for Cardiovascular Surgery,Russian Academy of Medical Sciences, 2012. 408 p. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Позняковский В.М., Чугунова О.В., Тамова М.Ю. Пищевые ингредиенты и биологически активные добавки. М.: ИНФРА-М, 2017.143 с.</mixed-citation><mixed-citation xml:lang="en">Poznyakovsky V.M., Chugunova A.A., Tamova M.Yu. Food ingredients and dietary supplements [Nutrition ingredients and biologically active food supplements] Мoscow, INFRAМ, 2017. 143p. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Vekovtsev A.A., Tokhiriyon B., Chelnakov A.A., Poznyakovsky V.M. Evidence for Effectiveness and Functional Properties of Specialized Product in Clinical Trial. // Human. Sport. Medicine. 2017, vol. 17, no. 3, pp. 94–101. doi: 10.14529/hsm170310.</mixed-citation><mixed-citation xml:lang="en">Vekovtsev A.A., Tokhiriyon B., Chelnakov A.A., Poznyakovsky V.M. Evidence for Effectiveness and Functional Properties of Specialized Product in Clinical Trial. Human. Sport. Medicine, 2017, vol. 17, no. 3, pp. 94–101. doi: 10.14529/hsm170310.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Технологический регламент ТС 027 / 2012 «О безопасности отдельных видов специализированной пищевой продукции, в том числе диетического, лечебного и диетического профилактического питания». URL: docs.cntd.ru/document/902352823.</mixed-citation><mixed-citation xml:lang="en">Tekhnologicheskii reglament TS 027 2012 O bezopasnosti otdelnykh vidov spetsializirovannoi pishchevoi produktsii v tom chisle dieticheskogo lechebnogo i dieticheskogo profilakticheskogo pitaniia [Manufacturing formula ТС 027 / 2012 Product safety of some specialized food products, including dietary, medical and preventive nutrition] Available at: docs.cntd.ru/document/902352823  (in Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
