The article highlights the results of a study of the nature of innovation changes in methods and forms of production management in the light of the main provisions of quality management system in accordance with the requirements of ISO 9001:2015. Presents the author's interpretation of key provisions of a modern system of quality management are highlighted in the General directions of development of the company's management examined the nature of institutional changes in the quality management system and the system of organization of production, as well as methodological approaches, methods and tools improving the organization of production processes. Analysis of changes based on the key provisions of the integrated model of management system qualities, allowed to reveal the contents of the provisions in the context of an enterprise management system and system of organization of production, to offer the author's interpretation of the concept of organization of production based on the principles and requirements of the quality management system, and to substantiate features of the quality management system as a special form of organization of production processes. According to the analysis of benefits at the enterprise the quality management system developed in accordance with the requirements of ISO 9001:2015, describes the objectives and tasks of the system of production organisation in the light of the recommendations of the integrated model of this system, learn how to change the patterns of development methods and forms of organization of production processes with regard to the content of the process approach recommended by the system management qualities as well as the interrelation of the concept of "knowledge management" and improving personnel management processes of enterprises with the aim of ensuring their competence in the field of maintenance and improvements in the quality of manufacturing processes, studied the problems of enterprises related to the implementation of key provisions of the integrated quality management system and proposed management recommendations to address.

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