Развитие биоинформационных методов исследования способствует глубокому изучению различных биологических объектов, в том числе животного и растительного происхождения, с целью получения из них препаратов, которые могут эффективно применяться в медицине и различных отраслях пищевой промышленности. Можно предположить, что результаты многочисленных исследований, демонстрирующих преимущества хлеба «на закваске» перед «дрожжевым» по ряду показателей (снижение гликемической нагрузки и аллергенных свойств белков, более высокая антиоксидантная активность, лучшая усвояемость минеральных веществ и др.), обусловлены наряду с другими факторами и наличием определенных биологических активных пептидов. Цель исследования – поиск, систематизация и анализ научно-технической информации, связанной с изучением протеолиза в полуфабрикатах хлебопекарного производства и высвобождением пептидов, их биологической активности. Проведенный анализ научно-технической литературы свидетельствует о том, что биологически активные пептиды находятся в центре внимания ученых всего мира. По-прежнему сохраняют актуальность исследования, направленные на способы их извлечения из разнообразного сырья, условия, от которых зависит количество и свойства высвободившихся или синтезированных биологически активных пептидов. Общим в патогенезе большинства хронических воспалительных заболеваний является участие окислительного стресса, связанного с продукцией активных форм кислорода. Поэтому пищевые антиоксиданты, содержащиеся в продуктах питания, в настоящее время представляют собой новую эффективную стратегию противодействия такому состоянию. В связи с этим особую актуальность приобретают исследования, направленные на выявление роли пептидов, содержащихся в пищевых продуктах, в том числе хлебобулочных изделиях на закваске, в профилактике ряда социально-значимых заболеваний, в первую очередь, заболеваний сердечно-сосудистой системы.

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