В работе представлена методика получения двухслойных плёнок на основе полиэлектролитного комплекса гиалуроната натрия и хитозана, ориентированных на применение в биомедицинских целях. Изучено влияние массового соотношения компонентов, последовательности нанесения слоёв и толщины плёночного материала на структуру, морфологию и механические свойства получаемых плёнок. Формирование полиэлектролитного комплекса подтверждено методом ИК-Фурье спектроскопии, выявившим характерные изменения полос поглощения функциональных групп полимеров. В ходе работы определены морфологические характеристики полученных полимерных плёнок методом оптической микроскопии и физико-механические характеристики при растяжении. Показано, что оптимальные свойства плёночного материала достигаются при массовом соотношении гиалуроновой кислоты и хитозана 1:7 и последовательности нанесения слоёв HA-Na → CH. Установлено, что увеличение толщины плёнки за счёт повышения объёма наносимых слоев приводит к существенному росту прочностных характеристик и относительного удлинения. Полученные результаты свидетельствуют о возможности целенаправленного регулирования свойств двухслойных плёнок на основе гиалуроната натрия и хитозана путём варьирования технологических параметров, что делает разработанные материалы перспективными для использования в качестве биомедицинских плёночных матриксов при травмах и повреждениях.

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